Vayalil founded Burjeel Holdings in Abu Dhabi in 2007 and assumed the additional role of CEO in 2026, while remaining chairman. The group employs over 14,100 people and serves over seven million patients annually. As of June 2026, it operates 20 hospitals within a network of 107 healthcare assets mainly in the UAE and Saudi Arabia with 1,784 beds. In 2025, it made $1.5 billion in revenues and had $1.8 billion in total assets. Vayalil is also founder and chairman of VPS Health. Forbes estimates his net worth at $1.8 billion as of August 2026.