Dimitrios Dosis assumed his current position at Mastercard in 2021, having been with the company since 2005. In May 2025, Mastercard announced the launch of a Cyber Resilience Center in Riyadh to support cyber resilience through education, global standards, and risk assessments. Riyad Bank joined as the first partner in the initiative. In the same month, the National Bank of Egypt and Mastercard signed an agreement with Mwasalat Misr Group to digitize public transport payments. Dosis is also a member of Mastercard’s management committee and serves on the boards of the Dubai International Chamber and the Athens Exchange Group.