Griffiths joined Dubai Airports in 2007 as its first CEO. Dubai Airports owns and operates the Dubai International Airport (DXB) and the Dubai World Central (DWC). DXB supports 193 destinations across 92 countries worldwide as of May 2022. It welcomed 29.1 million passengers in 2021 and handled 2.3 million tonnes of cargo. It launched its Terminal 3 in 2008. Dubai Airports opened DWC in 2010, which aims to become a global gateway with a capacity for over 160 million passengers per year. Before joining Dubai Airports, Griffiths was a board member for Virgin Travel Group for 14 years. Prior to that, he was the managing director of Gatwick Airport in London for more than three years.